Author(s) Details:
Pablo Hernán Sotelo
Biotechnology Department, Facultad de Ciencias Químicas, Universidad Nacional de Asunción, San Lorenzo 111421, Paraguay.
Arturo Vargas-Correa
Biotechnology Department, Facultad de Ciencias Químicas, Universidad Nacional de Asunción, San Lorenzo 111421, Paraguay.
This section is a part of the chapter: Strategies for Studying Antiviral Activity of Natural Products: From Screening to Mechanism Elucidation
This chapter explores various strategies for the study of antivirals derived from natural products, focusing on methodologies for virus quantification, design of biosensors for specific targets for antiviral evaluation, and strategies for investigating natural products that may impact multiple stages of the viral cycle. The chapter begins by discussing traditional screening methods that include viral load quantitation, which is an essential tool for evaluating antiviral activity.
Building on the foundation of viral quantification methods, this chapter describes the design and development of antiviral strategies targeting specific viral proteins or processes essential for viral production. These include the construction of sensors for viral enzymes, receptors, and structural proteins that serve as potential targets for antiviral intervention. Natural products are rich sources of bioactive compounds that can modulate these targets by inhibiting viral enzymes, blocking viral entry or fusion, or interfering with viral replication or assembly processes.
How to Cite
Sotelo, P. H. ., & Vargas-Correa, A. . (2025). Strategies for Studying Antiviral Activity of Natural Products: From Screening to Mechanism Elucidation. Pharmaceutical Science: New Insights and Developments Vol. 4, 1–17. https://doi.org/10.9734/bpi/psnid/v4/4496